Compatibility of Drug and Excipient: Faster and Easier By Means of Thermal Analysis and SuperPosition

DSC in Pharma R&D

Compatibility refers to harmony in a relationship, but is also an important terms in science, be it in medicine where only a compatible organ can be transplanted to a recipient, or in computing to refer to software packages that can be used together. This concept is also well-known in the pharamceutical field: Two components (e.g., … Read moreCompatibility of Drug and Excipient: Faster and Easier By Means of Thermal Analysis and SuperPosition

IQ and OQ – What Does This Mean for Thermal Analysis Users?

4Q - Instrument qualification

– In particular for users of differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) – Installation qualification (IQ) and operational qualification (OQ) are part of the so-called analytical instrument qualification (AIQ) process at the user´s lab to confirm that an instrument is properly installed, works correctly and yields the expected results. A key term in … Read moreIQ and OQ – What Does This Mean for Thermal Analysis Users?

How Quality Control and Failure Analysis of PP Effectively Prevent Scrapping of Goods

by Jinyan Li, Liang Xu and Dr. Zhiqiang Zeng; NETZSCH Scientific Instruments Trading, China

Do you need a plastic part or a film with very specific properties – such as temperature stability coupled with dimensional stability accurate to a hundredth of a millimeter and UV resistance – otherwise it cannot be used for its intended purpose? But how can you check whether all requirements have been met and, in addition, how can failures be analyzed?
Only if such questions are under control is it possible to permanently reduce the number of rejects. NETZSCH Analyzing & Testing offers a range of thermoanalytical methods for this purpose.

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Blogging: Concentrated knowledge for our customers!

A corporate blog is used by companies as a marketing and communication tool. Corporate blogging is therefore a tactic of companies to attract attention, to be found on search engines and to become more visible, to generate leads and to reach new users and to communicate with them. A corporate blog that is strategically set … Read moreBlogging: Concentrated knowledge for our customers!

NETZSCH EPS – A New and Affordable Standard Material for Testing Thermal Conductivity with HFM Instruments

The heat flow meter (HFM) method is mainly used to test thermal conductivity and thermal resistance of insulation samples. It is not an absolute method, therefore, the heat flow meter output needs to be calibrated with a standard material. NETZSCH-Gerätebau GmbH has recently qualified its own factory standard for calibration and validation of heat flow … Read moreNETZSCH EPS – A New and Affordable Standard Material for Testing Thermal Conductivity with HFM Instruments

Optimizing Reactive Injection Molding with In-line Sensors

NETZSCH and KISTLER, two family owned companies, offer the most advanced process package for reactive injection molding targeting zero waste production while at the same time a maximum in efficiency with an increased throughput is enabled.

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Sub-ambient DMA Measurements down to -70°C without Using LN2

Many investigations in the field of polymers with lower stiffness require a measurement start below room temperature. As an alternative to existing solutions with Vortex tube and liquid nitrogen cooling, NETZSCH now offers the new compact AIC 80 intracooler for DMA measurements that works with chilled air. It reliably cools samples to -70°C without the use of liquid nitrogen.

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How to use TGA for the quality control of carbon fiber-reinforced polymers

CFRP_TGA_quality control_netzsch

The determination of fiber volume fraction is crucial for the quality control of carbon fiber-reinforced polymers (CFRP) in order to ensure their favorable mechanical and physical properties for the use in aerospace, wind energy and automotive sectors. A new thermogravimetric testing method, published by Dominik Grund in the journal “Polymer Testing”, considers heating rate, analysis atmosphere and sample size to efficiently ensure high quality of the material. This editorial summarizes the steps for the use of TGA in the quality control of carbon fiber-reinforced polymers.

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Good Stability Versus Good Tabletability: The Choice of Modification

Many pharmaceutical solids exhibit polymorphism, i.e., the ability of a substance to exist in different crystalline forms. The polymorphic form can have significant influence on pharmaceutical processing and can, for example, affect grinding, granulation and tabletability. A DSC measurement allows for the characterization of the present modification. Here, different modifications of paracetamol are distinguished by means of DSC.

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Lambda-Measurement and the Fight against Condensing Humidity

Insulating Materials

Humidity plays a major role in the quality assurance of insulating materials. Ignorance in dealing with condensation and establishing good measurement conditions can result in unexpected measurement results. This article shows methods, that helps to overcome condensation issues in the quality assurance of thermal insulation materials.

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