- Humidity of the environment storage;
- Particle size;
Compactibility is the ability of a powder to form a mechanically strong tablet, whereas compressibility is the ability of a powder to be compressed and consequently be reduced in volume . The manufacture of tablets requires a well compressible API (Active Pharmaceutical Ingredient) or its combination with adequate excipients responsible for the good compressibility behavior of the formulation. In this case, a main challenge is to find the excipients that don´t affect the properties, stability, efficacy of the active ingredient (please click here to get more information about drug-excipient compatibility). Some elements can influence the compressibility behavior as well as the properties of the compact:
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