Paracetamol (acetaminophen) is the most commonly used medication for pain and fever in both the United States and Europe. However, it is not worth getting a headache when you think about its physicochemical properties. Thermal analysis, and especially differential scanning calorimetry (DSC), is of great help.
From the chemical point of view, diamonds are just made of carbon. The phenomenon that chemical elements can occur in different forms within the same phase, i.e., in different structural modifications, is called allotropy. Due to the relationship between crystal modification and melting point, Differential Scanning Calorimetry (DSC) is ideally suited to discriminate between different polymorphic forms. A more general term for chemical compounds is polymorphism.
Thermal Analysis provides powerful analytical methods for research, development and quality control of active pharmaceutical ingredients (APIs), excipients and formulations. Rheology perfectly complements the analytical equipment of your laboratory. Read more on the wide range of applications of DSC and Kinexus!
NETZSCH North America Commercial Testing Laboratory has set up a series of live demos based on questions we frequently hear in the field, at conferences and exhibitions about how our instruments work and the best measurements can be made. These demos are the short and sweet! Read more about the series and register for the first episode on 30 June 2020!
Alucent Biomedical Inc. is a biomedical company dedicated to developing its breakthrough Natural Vascular Scaffolding (NVS) technology for the treatment of vascular disease. Multiple sample preparation techniques were evaluated to investigate a method that could alleviate signal artifacts attributed to sample movement during heating. Learn how the sample is prepared to achieve accurate and reproducible thermograms for biological tissue.
Compressibility of a pharmaceutical substance can lead to changes in its crystal structure, and thus in its properties (bio-availability, flowability, …). A DSC measurement verifies the quality of the product after compression.
In seven free webinars, we covered relevant topics from the features of our software, Proteus® and LIMS support from NETZSCH, to our different coupling solutions and how to measure shear viscosity. Read this quick summary and gain access to all webcasts!
PMMI (Polymethacrylmethylimide) is a thermoplastic polymer. As it is an amorphous polymer, it features high transparency. The case study describes how thermal analysis methods can be employed to discover everything about the material.
Bringing cost, material, production process and quality successfully together is one of the key objectives in the injection molding industry. If the production process is not correct or if the material does not adhere to the specified requirements, low quality and thus scrap production is the consequence. Ideally, all of these four factors should be able to be managed in order to avoid scrap production. Thermal analysis methods offer valued approaches.
Knowledge of the thermal properties of the material is crucial for producing thermoplastic parts. However, materials are not always delivered with sufficient information on all properties. Thermal analysis instruments are suitable to find the most important parameters by yourself. But the instrument is only the first step. The software is equally important. Here are two examples how Proteus® can help achieve faster results.