Thermische Analyse und Rheologie beinhalten essentielle analytische Methoden, die die Entwicklung von Arzneimitteln unterstützen und deren Qualität sicherstellen. Erfahren Sie in unserem neuen Video, wie NETZSCH Analysieren & Prüfen zur Entwicklung und Qualitätskontrolle von Arzneimitteln beiträgt!
Thermal Analysis and Rheology comprise essential analytical methods supporting the development of pharmaceuticals and ensuring their quality. Watch our new video and learn how NETZSCH Analyzing & Testing contributes to the development and quality control of pharmaceuticals!
Our video series “Expert Insights into Substance Analysis” continues! Today, Dr. Joana Pinto (Research Center Pharmaceutical Engineering GmbH) introduces three examples studying the interaction of drugs and excipients using thermal analysis.
Unsere Videoserie “Experteneinblicke in die Substanzanalyse” geht weiter! Dr. Joana Pinto (Research Center Pharmaceutical Engineering GmbH) stellt drei Beispiele vor, in welchen die Wechselwirkung von Wirkstoffen und Hilfsstoffen mit Hilfe von Thermischer Analyse untersucht wird.
Thermogravimetry (TGA) is frequently applied for the compositional analyses of such materials as, for example, fiber-reinforced polymer composites. The residual mass at the end of a TGA experiment reflects the filler or glass fiber content as well as the presence of impurities. By using a relatively large sample volume in a top-performing thermobalance along with the intelligent Proteus® software by NETZSCH, it is possible to detect ultra-small residual masses with concentrations down to the ppm (= 10-6) range! Such small concentrations can be illustrated by a little bird with a mass of a few grams sitting on the back of an elephant weighing a few tons.
Raw material identification or incoming goods inspection is of paramount importance for the quality and safety of drug products, wherever chemical substances are used in the pharmaceutical industry – maybe as an educt of chemical reactions or as a basis for further processing.
From the chemical point of view, diamonds are just made of carbon. The phenomenon that chemical elements can occur in different forms within the same phase, i.e., in different structural modifications, is called allotropy. Due to the relationship between crystal modification and melting point, Differential Scanning Calorimetry (DSC) is ideally suited to discriminate between different polymorphic forms. A more general term for chemical compounds is polymorphism.
Thermal Analysis provides powerful analytical methods for research, development and quality control of active pharmaceutical ingredients (APIs), excipients and formulations. Rheology perfectly complements the analytical equipment of your laboratory. Read more on the wide range of applications of DSC and Kinexus!
NETZSCH North America Commercial Testing Laboratory has set up a series of live demos based on questions we frequently hear in the field, at conferences and exhibitions about how our instruments work and the best measurements can be made. These demos are the short and sweet! Read more about the series and register for the first episode on 30 June 2020!
Compressibility of a pharmaceutical substance can lead to changes in its crystal structure, and thus in its properties (bio-availability, flowability, …). A DSC measurement verifies the quality of the product after compression.